- Oct. 17 Presbyterian (Exhibition)
- Nov. 3 New Hampshire
- Nov. 7 Gardner-Webb
- Nov. 11 Morehead State
- Nov. 15 Georgetown
- Nov. 17 North Alabama
- Nov. 21 West Virginia (Charleston Classic – Charleston, S.C.)
- Nov. 23 Georgia/Xavier (Charleston Classic – Charleston, S.C.)
- Nov. 28 Alabama A&M
- Dec. 3 Alabama (2025 ACC/SEC Challenge – Tuscaloosa, Ala.)
- Dec. 9 BYU (Jimmy V Classic – New York, N.Y.)
- Dec. 13 Mercer
- Dec. 16 South Carolina
- Dec. 21 Cincinnati (Greenville Winter Invitational – Greenville, S.C.)
The ACC schedule is forthcoming.
2025-26 Clemson’s ACC Opponents
- Rival (Home and Away): Georgia Tech
- Repeats (Home and Away): Pittsburgh
- Home Only: SMU, Florida State, Miami, NC State, Virginia Tech, Louisville, Boston College
- Away Only: California, Stanford, Wake Forest, North Carolina, Duke, Notre Dame, Syracuse
- No Play: Virginia